Understanding chronic bronchitis and living life with COPD GoHealth Urgent Care Chronic Obstructive Pulmonary Disease (COPD) Montgomery Pulmonary Consultants Vaping' Increases Odds of Asthma and COPD Johns Hopkins Medicine The Role of Smoking in the Mechanisms of Development of Chronic Obstructive Pulmonary Disease and Atherosclerosis COPD is a progressive, largely irreversible airflow limitation characterized by chronic cough, sputum production, and dyspneamost commonly due to smoking. Spirometry (FEV FVC < 0.7) confirms diagnosis; smoking cessation is the most effective