Vaping Devices (Electronic Cigarettes) DrugFacts National Institute on Drug Abuse (NIDA) Smoking vs vaping what are the key differences? Evapo Some E Cigarette Flavors May Be More Harmful Than Others The Atlantic E Cigarettes and Cardiovascular Health German Heart Centre Smoking and vaping are often compared, but neither is harmless. While they work differently, both can expose the lungs to addictive nicotine and harmful chemicals that impact breathing and overall health. Smoking