CJC 1295 + Ipamorelin vs IGF 1 LR3 for Muscle Growth IGF 1 LR3 forces receptor desensitization in 4 6 weeks, requiring months off before you can use it again. CJC 1295 and Ipamorelin amplify your natural CJC 1295 + Ipamorelin Sculpt Your Body and Boost Energy Ipamorelin and CJC 1295: Interactions with The Pituitary Gland Peptides are getting more hype than almost anything in longevity medicine right now, but the reality behind the excitement is more nuanced. Outside of a few well studied categories, most peptides still lack Activation of the GH IGF 1 axis by CJC 1295, a long acting GHRH analog, results in serum protein profile changes in normal adult subjects ScienceDirect