Metabolome and Metagenome Signatures Underlying the Differential Resistance of Percocypris pingi, Crucian Carp, and Yellow Catfish to Ichthyophthirius multifiliis Infection PDF) Histamine chloramine reactivity with thiol compounds, ascorbate, and methionine and with intracellular glutathione Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification Neurobiologix GI Hist Support DAO supplement Mast cells are hypersensitive immune cells that release histamine and other inflammatory mediatorsoften in response to oxidative stress, environmental toxins, and immune imbalance. Many patients with MCAS have low levels of glutathione.