Injection Techniques Step by Step Guide 1. Intramuscular Injection (IM) 90 Angle Needle Position: Perpendicular to the skin (90 angle) Target Site: Muscle layer Common Sites: Deltoid, Vastus Lateralis, B12 Shots at Home: How, Where & How Often to Inject Yourself AZ IV Medics Compounded Methylcobalamin (Vitamin B12) Injection, 5mg mL Sandoz Vitamin B12 Injectable Solution 1000 mcg 10 mL Vitamin B12 Not All Shots Are Created Equal Your Quick Guide to Injection Types , Ever wondered why some shots go in your arm muscle and others just under the skin? Heres the breakdown:, Intramuscular (IM)