AD :: Annals of Dermatology Oral Melanotic Macule: Symptoms and Treatment Skinsight Spotty lips. These are labial melanotic macules, kinda like freckles on the lips. They are mostly due to age and sun exposure, but sometimes they run in families and are associated with Emerging Threat: Melanotan, Repackaging, and Online Sales Does anyone know what this black mark on my lip is? Started last August so it's I've had it nearly a year, was living in Spain at the time for 6 months