An Optimized Dihydrodibenzothiazepine Lead Compound (SBI 0797750) as a Potent and Selective Inhibitor of Plasmodium falciparum and P. vivax Glucose 6 Phosphate Dehydrogenase 6 Phosphogluconolactonase Antimicrobial Agents and Chemotherapy Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target PLOS Medicine X ray structure of glutathione S transferase from the malarial parasite Plasmodium falciparum PNAS The essential host genome for Cryptosporidium survival exposes metabolic dependencies that can be leveraged for treatment: Cell PfK13 associated artemisinin resistance slows drug activation and enhances antioxidant defence, which can be overcome with sulforaphane bioRxiv
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glutathione parasites The Architecture of Thiol Antioxidant Systems among Invertebrate Parasites