Downregulation of Glutathione Mediated Detoxification Capacity by Binge Drinking Aggravates Acetaminophen Induced Liver Injury through IRE1 ER Stress Signaling Acetaminophen, also known as Tylenol, is used to help with pain & to reduce fever. However, taking too much acetaminophen can be harmful to the liver which filters out toxins & Pharmacology of paracetamol Deranged Physiology Dr. Laura E. Riley joined @GoodMorningAmerica recently to clear up some lingering confusion about Tylenol (acetaminophen) use during pregnancy. A new study from the University of London found that acetaminophen is safe Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: