Frontiers Age and APOE affect L carnitine system metabolites in the brain in the APOE TR model L CARNITINE Machine learning guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis: Cell Metabolism In a meta analysis of 21 RCTs, L carnitine supplementation improved several outcomes related to cardiometabolic health in people with type 2 diabetes. However, the certainty of the evidence and the clinical importance of l carnitine, a friend or foe for cardiovascular disease? A Mendelian randomization study BMC Medicine Springer Nature Link