Lip Pigmentation Treatment in Singapore Pigmented Lesions of the Oral Mucosa Pocket Dentistry In the process of removing a Labial Melanotic Macule. A Labial Melanotic Macule is a well defined, oval, brown to black, flat patch on the central third of the lower lip, as seen Pathology Outlines Melanotic macule Definition of melanocytic macules associated with Peutz Jeghers syndrome NCI Dictionary of Genetics Terms NCI