Labial lentigines, also called labial melanotic macules, is a benign skin condition that is more common in individuals with darker skin. They most often appear during adulthood although they can develop at Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Diseases of the lips Clinics in Dermatology Does anyone know what this black mark on my lip is? Started last August so it's I've had it nearly a year, was living in Spain at the time for 6 months Search Results: Oral Mucosal Lesion Single skin lesion, Mucosal lip, Oral brown macule, 40 49 year old Male