Biotransformation of drug PPTX GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY Glutathione Conjugation! Conjugation With Glutathione and Mercapturic Acid Formation Biotransformation of Drugs Frontiers Glutathione S conjugates as prodrugs to target drug resistant tumors
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glutathione conjugation reaction Glutathione Conjugate - an overview