Mast cells are hypersensitive immune cells that release histamine and other inflammatory mediatorsoften in response to oxidative stress, environmental toxins, and immune imbalance. Many patients with MCAS have low levels of glutathione. The Gut Histamine Connection: How Butyrate Supports a Balanced Respons How to fix Histamine Intolerance? by Anastasis Tzanis Coincidentally, these are also the most commonly recommended supplements as well! Supplements can feel like the ultimate paradox when you have histamine issues. On one hand, your body may need something like Histamine Supplement Stark Pharmacy